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Medically reviewed by Dr. Emmanuel Noel Cruz Tancinco, MD

The Skinny Shot is a weekly compounded injection that combines methionine, inositol and choline (MIC) with vitamins B5, B6 and B12, L-carnitine and L-arginine, plus a little lidocaine for comfort. Explore clinician-guided treatment with transparent pricing, online provider review and licensed pharmacy fulfillment.

  • MIC + B-complex formula with L-carnitine, L-arginine and lidocaine for a more comfortable shot.
  • Weekly at-home injection; home injection kit included.
  • Free shipping in discreet packaging.

Choose your plan

Same price at every dose

$89/moSave $360

$1,068 billed every 12 months

Get started · $89/mo

Provider review included in your plan · Prescribed only when appropriate

  • Free shipping
  • Compounded in the U.S.A.

Compounded medications are not FDA-approved. The FDA does not review compounded medications for safety, effectiveness, or quality before they are marketed. A licensed provider determines whether a compounded medication is appropriate based on an individual patient’s medical needs.

What is the Skinny Shot?

The Skinny Shot is a weekly compounded injection that combines methionine, inositol and choline (MIC) with vitamins B5, B6 and B12, L-carnitine and L-arginine, plus a little lidocaine to make the shot more comfortable. It's prescribed online after a licensed provider reviews your health history, and it's used alongside a reduced-calorie diet and regular activity.

What's in the Skinny Shot?

Methionine, inositol and choline (MIC); vitamins B5 (dexpanthenol), B6 (pyridoxine) and B12 (cyanocobalamin); the amino acids L-carnitine and L-arginine; and lidocaine, a numbing agent added for a more comfortable injection.

How is the Skinny Shot different from a lipotropic (MIC + B12) shot?

Both contain MIC and vitamin B12. The Skinny Shot adds vitamins B5 and B6, L-carnitine, L-arginine and lidocaine. If you want the simpler formula, see lipotropic injections.

Skinny Shot at a glance

Treatment
Weight Loss
Form
Injection
Prescription
Required, after clinician review
Price
From $89/mo
Shipping
Free and discreet
Availability
Online in 25 states

Support your weight-management plan, with clinician guidance.

The Skinny Shot program pairs a prescribed weekly MIC + B-complex injection with clinician guidance, alongside a reduced-calorie diet and physical activity.

It combines methionine, inositol and choline (MIC) with vitamins B5, B6 and B12, L-carnitine and L-arginine, nutrients the body uses in processing fat and in normal energy metabolism, plus lidocaine for a more comfortable shot.

The basics

What Is the Skinny Shot?

The Skinny Shot is a prescription, compounded injection that you give yourself at home once a week. It builds on the classic lipotropic (MIC + B12) shot with extra B vitamins, two amino acids and a numbing agent.

What's in it

Methionine, inositol and choline (MIC); vitamins B5 (dexpanthenol), B6 (pyridoxine) and B12 (cyanocobalamin); L-carnitine and L-arginine; and lidocaine.

How the formula works

Choline helps the liver package and move fat out, and methionine and inositol are involved in the same process. Vitamins B5, B6 and B12 support normal energy metabolism. L-carnitine helps carry fatty acids into cells' mitochondria, where they're used for energy, and L-arginine is an amino acid the body uses to make nitric oxide, which helps blood vessels relax. Lidocaine numbs the injection site for a more comfortable shot.

Why a provider consultation matters

The Skinny Shot is available only by prescription. A licensed provider reviews your medical history, current medications and goals to decide whether it's appropriate and to set a safe plan. You can start the online consultation here.

What are the potential benefits of the Skinny Shot?

What's in it

A compounded injection of methionine, inositol and choline (MIC) with vitamins B5, B6 and B12, L-carnitine, L-arginine and lidocaine, given at home once a week or on the schedule your provider sets.

Helps the liver handle fat

Choline helps the liver package and move fat out, and methionine and inositol are involved in the same process.

Energy metabolism

Vitamins B5, B6 and B12 support normal energy metabolism, the way your body turns food into usable energy.

L-carnitine

L-carnitine helps carry fatty acids into your cells' mitochondria, where they're used for energy.

L-arginine

L-arginine is an amino acid your body uses to make nitric oxide, which helps blood vessels relax.

A more comfortable shot

A small amount of lidocaine, a numbing agent, is added so the weekly injection is more comfortable.

Benefit statements describe what the ingredients do in the body and are not guarantees of results. A licensed provider can help set realistic expectations.

Step by step

How to use the Skinny Shot

General tips. Always follow the directions from your provider and the pharmacy label.

Once a week

Inject once a week, or on the schedule your provider sets.

Inject under the skin

Use the stomach area or thigh, following the instructions in your home kit.

Rotate injection sites

Use a different spot each time to reduce soreness, redness, or swelling.

Clean technique

Wash your hands, wipe the vial top and your skin with an alcohol pad, and use a new needle every time.

Store it as labeled

Keep vials as the pharmacy label directs and out of reach of children.

Pair it with your routine

The Skinny Shot is meant to support a reduced-calorie diet and regular activity.

Dispose of needles safely

Put used needles in a sharps container, never in household trash.

Begin your journey with DripVitals

Every wellness journey is different, and so are our customized Skinny Shot treatment plans.

Get started
  1. STEP #1

    Select your treatment

    Choose a plan that fits your needs and complete a medical intake form for review by providers.

  2. STEP #2

    Provider evaluation

    A licensed provider reviews your history to determine if the Skinny Shot is right for you — all online.

  3. STEP #3

    Your medication, delivered

    If approved, your Skinny Shot ships in 3–5 days in discreet packaging, so you can start your journey.

Skinny Shot Safety, Side Effects, and Eligibility

Like any medical treatment, the Skinny Shot carries potential risks, and it isn't appropriate for everyone. Reviewing the following with a licensed provider is an essential part of treatment.

Potential side effects

Reported effects are generally mild and may include injection-site reactions (redness, soreness, swelling), nausea, an upset stomach or headache. Report any unusual or persistent symptoms to your care team, and seek prompt medical attention for signs of an allergic reaction. For tips on easing common side effects, see our guide to lipotropic injection side effects.

Who Should Not Use the Skinny Shot?

The Skinny Shot is generally not recommended during pregnancy or breastfeeding, or for anyone with an allergy to an ingredient, including lidocaine or other numbing medicines, B vitamins or cobalt. Tell your provider about liver or kidney disease, low blood pressure, or a seizure disorder. Your provider reviews your history and will decline treatment when it isn't appropriate.

Drug-interaction review

Share a complete list of your prescriptions, over-the-counter products, vitamins and supplements during your consultation, especially blood-pressure medicines, nitrates or erectile dysfunction medicines, so your provider can check for potential interactions. Never start, stop or change a medication without talking to a licensed provider.

When to contact a medical provider, and why results vary

Contact your provider if you experience side effects, have questions about dosing, or notice anything unexpected. Individual results vary based on your health, the plan prescribed, and many factors outside any single treatment, and no specific outcome is guaranteed.

Compounded medications are not FDA-approved. The FDA does not review compounded medications for safety, effectiveness, or quality before they are marketed. A licensed provider determines whether a compounded medication is appropriate based on an individual patient’s medical needs.

Comparison

Skinny Shot vs. Lipotropic Injections

Both are weekly MIC injections. The Skinny Shot is the fuller formula; lipotropic injections are the simpler MIC + B12 shot. A licensed provider can help you decide which fits your goals.

Skinny ShotThis treatment

Skinny Shot

Lipotropic Injections

Lipotropic Injections

MIC (methionine, inositol, choline)YesBoth
Vitamin B12YesBoth

Vitamins B5 and B6

Yes

Vitamins B5 and B6

No

L-carnitine and L-arginine

Yes

L-carnitine and L-arginine

No

Lidocaine for comfort

Yes

Lidocaine for comfort

No

How it's takenWeekly shot under the skinBoth

Plans from

$89/mo*

Plans from

$69/mo*

Prefer the classic formula? See lipotropic injections.

Comparison

Skinny Shot vs. Oral Fat-Burner Pills

A common question is whether to choose an injection or oral fat-burner pills. The main differences are what's in them, how they're taken, and how they're regulated.

Skinny ShotThis treatment

Skinny Shot

Oral Fat-Burner Pills

How it’s taken

Subcutaneous injection

How it’s taken

Swallowed pill or capsule

What’s in it

MIC, vitamins B5, B6 and B12, L-carnitine, L-arginine and lidocaine

What’s in it

Varies by product; often caffeine or other stimulants

Medical oversight

Prescription after a licensed provider’s review

Medical oversight

Sold over the counter, usually without medical review

Regulation

Prepared by a licensed compounding pharmacy; not FDA-approved

Regulation

Dietary supplement; not reviewed by the FDA for effectiveness

Neither option is right for everyone — the right choice depends on your medical history and goals, and a licensed provider can help you decide.

Comparison

Skinny Shot vs. GLP-1 Treatment

These are different categories of care. The Skinny Shot provides nutrients and amino acids and is used alongside diet and exercise, while semaglutide and tirzepatide are prescription weight-loss medications. Some people use both as part of one plan; a licensed provider can help you decide. Explore all weight-loss treatment options.

Skinny ShotThis treatment

Skinny Shot

GLP-1 Treatment

GLP-1 Treatment

Primary purpose

Nutrient support (MIC + B-complex)

Primary purpose

Prescription weight-loss medication

Ingredients

MIC, B5, B6, B12, L-carnitine, L-arginine, lidocaine

Ingredients

Semaglutide or tirzepatide

Provider reviewRequiredBoth

How it's taken

Weekly shot

How it's taken

Weekly shot (or daily tablet)

Best for

Nutrient support within a broader plan

Best for

Clinically appropriate weight loss

Why Choose a Clinician-Guided Skinny Shot Treatment Plan?

  • Structured dosing and check-ins with your care team
  • Includes support for nutrition, sleep, and movement goals
  • 24/7 access to messaging with your care team
  • Monthly check-ins and as-needed dosage adjustments when clinically appropriate
  • Plans designed to stay affordable across commitment lengths

Program

Skinny Shot Cost & What’s Included

A DripVitals Skinny Shot program is a clinician-guided subscription that bundles your care and medication. Depending on what your provider prescribes, it typically includes:

  • Online medical consultation and licensed-provider review
  • Skinny Shot vialYour prescribed medication from a licensed pharmacy
  • Home injection supplies, where applicable
  • Free, discreet shipping
  • Ongoing messaging access to your care team
  • Follow-up check-ins with dose adjustments when clinically appropriate
  • A subscription you can cancel at any time
  • Ready when you areStart your evaluation

Simple, transparent pricing

Every plan includes your provider consultation, medication if prescribed, home injection supplies, and free discreet shipping. Cancel anytime.

Monthly

$119/mo

$119 billed monthly. Cancel anytime.

Choose 1 month
Most popular

Quarterly

$109/mo

$327 billed every 3 months

Save $30

Choose 3 months

Semi-annual

$99/mo

$594 billed every 6 months

Save $120

Choose 6 months
Best value

Annual

$89/mo

$1,068 billed every 12 months

Save $360

Choose 12 months

*Monthly rates reflect plan length: $109/mo billed $327 every 3 months, $99/mo billed $594 every 6 months, $89/mo billed $1,068 every 12 months. A licensed provider determines whether treatment is appropriate.

Dr. Emmanuel Noel Cruz Tancinco, MD, medical reviewer

Medically Reviewed

Dr. Emmanuel Noel Cruz Tancinco, MD

Attending Physician · ABAARM · FAAMM · DABOM

Board-certified in obesity medicine and internal medicine, with practice focused on hormone optimization, metabolic medicine, and longevity-focused care — licensed in all 25 states we serve.

  • Hormone Optimization
  • Obesity & Metabolic Medicine
  • Longevity-Focused Care
  • Functional Medicine
Education & certifications
  • American Board of Anti-Aging and Regenerative Medicine (ABAARM)
  • Anti-Aging Metabolic Medicine, American Academy of Anti-Aging Medicine
  • American Board of Obesity Medicine (DABOM)
  • American Board of Internal Medicine
  • The Institute for Functional Medicine
  • Bioidentical Hormone Replacement Therapy certified
  • Peptide Certification / Member, International Peptide Society
  • Integrative Gastroenterology, Endocrinology, Cardiology & Neurology Certification, The George Washington University School of Medicine and Health Sciences
  • Member, The American Academy of Anti-Aging Medicine (A4M)
  • Member, American College of Physicians

This page was reviewed for medical accuracy. Treatment decisions are made by a licensed provider after reviewing each patient’s medical history.

Important safety information

Skinny Shot: Guides & Further Reading

    Skinny Shot: Frequently Asked Questions

    Clear answers about the Skinny Shot — what it is, what's in it, safety, and how the program works.

    What is the Skinny Shot?

    The Skinny Shot is a weekly compounded injection that combines methionine, inositol and choline (MIC) with vitamins B5, B6 and B12, L-carnitine and L-arginine, plus a little lidocaine to make the shot more comfortable. It's prescribed online after a licensed provider reviews your health history, and it's used alongside a reduced-calorie diet and regular activity.

    What's in the Skinny Shot?

    Methionine, inositol and choline (MIC); vitamins B5 (dexpanthenol), B6 (pyridoxine) and B12 (cyanocobalamin); the amino acids L-carnitine and L-arginine; and lidocaine, a numbing agent added for a more comfortable injection.

    How is the Skinny Shot different from a lipotropic (MIC + B12) shot?

    Both contain MIC and vitamin B12. The Skinny Shot adds vitamins B5 and B6, L-carnitine, L-arginine and lidocaine. If you want the simpler formula, see lipotropic injections.

    Does the Skinny Shot help with weight loss?

    The Skinny Shot is not an FDA-approved weight-loss drug and is not a substitute for diet and exercise. It's used within a clinician-guided program to support the body's normal fat-metabolism pathways alongside healthy eating and activity. Results vary from person to person, and your provider can set realistic expectations for your situation.

    Is the Skinny Shot FDA-approved?

    No. The Skinny Shot is compounded by a licensed pharmacy for each individual prescription, and compounded medications are not FDA-approved.

    What are the possible side effects?

    Reported side effects are generally mild and may include soreness, redness or swelling where you inject, nausea, an upset stomach or headache. Report anything unusual or lasting to your care team, and get prompt medical care for signs of an allergic reaction.

    Who should not use the Skinny Shot?

    It isn't right for everyone. It's generally not prescribed during pregnancy or breastfeeding, or for anyone allergic to an ingredient, including lidocaine or other numbing medicines. Tell your provider about liver or kidney disease, low blood pressure, a seizure disorder, and every medicine you take.

    How often do you take the Skinny Shot?

    Most plans use one 1 mL shot a week, under the skin of the stomach area or thigh. Your provider sets your exact schedule and can adjust it at follow-ups.

    Why does the Skinny Shot contain lidocaine?

    Lidocaine is a numbing agent. A small amount is added so the weekly shot is more comfortable. If you've ever reacted to a numbing medicine, tell your provider during your intake.

    Can I use the Skinny Shot with semaglutide or tirzepatide?

    There's no well-known interaction between them, and some people use both as part of one plan. Your provider reviews everything you take and decides what fits your goals.

    How much does the Skinny Shot cost?

    Skinny Shot plans come in four lengths: $119/month billed monthly, $109/month on the 3-month plan (billed $327), $99/month on the 6-month plan (billed $594), and $89/month on the 12-month plan (billed $1,068). Longer plans lower the monthly price.

    Is a consultation required?

    Yes. The Skinny Shot requires a prescription, so a licensed provider reviews your health information online before anything is dispensed. If treatment isn't appropriate for you, the provider won't prescribe it.

    Disclaimer

    Only available if prescribed after an online consultation with a healthcare provider. Plans are offered as a subscription service which can be canceled at any time. Actual product packaging may appear differently than shown. Physicians may prescribe compounded medications as needed to meet patient requirements. The FDA does not review or approve any compounded medications for safety or effectiveness. The statements on this page have not been evaluated by the FDA. Results may vary. If you notice any side effects while using this treatment, contact your healthcare provider immediately.

    Start your online evaluation

    Skinny Shot from $89/mo. A licensed clinician reviews your answers.