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NAD+ Face Cream Online

Medically reviewed by Dr. Emmanuel Noel Cruz Tancinco, MDLast reviewed October 13, 2026

NAD+ face cream is a compounded topical skincare treatment that delivers nicotinamide-based ingredients to the skin to support a smoother, healthier-looking complexion. Explore clinician-guided NAD+ face cream with transparent pricing, online provider review, and licensed pharmacy fulfillment.

  • A nicotinamide-based topical that supports skin barrier and a smoother look.
  • A topical cream applied directly to the face, as directed.
  • Free shipping in discreet packaging.

As low as

$119/mo

Get started · $119/mo

Provider review included in your plan · Prescribed only when appropriate

  • Free shipping
  • Licensed clinicians
  • Cancel anytime

Compounded medications are not FDA-approved. The FDA does not review compounded medications for safety, effectiveness, or quality before they are marketed. A licensed provider determines whether a compounded medication is appropriate based on an individual patient’s medical needs.

What is NAD+ face cream?

NAD+ face cream is a compounded topical skincare product built around nicotinamide.

What are the potential benefits of NAD+ face cream?

Individual results vary.

Is NAD+ face cream the same as NAD+ injections or IV?

No. This is a topical cream that acts at the surface of the skin. It is not the same as systemic NAD+ therapies (injections, IV, or nasal) that aim to affect the whole body.

NAD+ Face Cream at a glance

Treatment
Skin
Form
Topical
Prescription
Required, after clinician review
Price
From $119/mo
Shipping
Free and discreet
Availability
Online in 35 states

Skin Support, With Clinician Guidance

The NAD+ face cream program is designed to support skin concerns with clinician guidance.

The basics

What Is NAD+ Face Cream?

NAD+ face cream is a compounded topical skincare product applied to the face. It is built around nicotinamide (a form of vitamin B3) and related NAD+-precursor ingredients, which are widely used in skincare to support the skin barrier and a smoother, more even-looking complexion. Because it is compounded, this specific formulation is not an FDA-approved product.

What NAD+ is in skincare

Nicotinamide is a well-studied skincare ingredient. Applied topically, it can help support the skin’s barrier function, help retain moisture, and is associated in research with a more even-looking tone and the appearance of fine lines. NAD+ precursors are included in this formulation for their role in skin-cell energy pathways. Topical products act at the surface of the skin and do not work the same way as systemic NAD+ therapies.

How it is used

The cream is applied to clean, dry facial skin as directed by your provider — typically once or twice daily. Results are gradual and build with consistent use. A licensed provider determines whether it is appropriate based on your skin and health history.

Why a provider consultation matters

NAD+ face cream is available only after review by a licensed provider, who confirms it is appropriate for your skin.start the online consultation here.

What are the potential benefits of NAD+ face cream?

Smoother, more even look

Nicotinamide is associated with a smoother, more even-looking complexion.

Barrier and moisture

Supports the skin barrier and helps skin retain moisture.

Less redness

Nicotinamide is associated with less visible redness and blotchiness.

Fuels skin cells

Nicotinamide is a form of vitamin B3 that skin cells use to make NAD+.

Refined-looking pores

Studied for minimizing the look of pores and uneven texture.

Benefit These statements describe general skincare research and are not claims of specific outcomes. Evidence for evidence on topical NAD+ skincare is still evolving, and results vary.

Step by step

How to use NAD+ face cream

General tips. Always follow the directions from your provider and the pharmacy label.

Start with clean skin

Apply to clean, dry facial skin.

Once or twice a day

Use it once or twice daily, as your provider directs.

A small amount

A thin layer is enough. Smooth it over the face, avoiding the eyes and lips.

Sunscreen in the morning

In the daytime, follow with sunscreen as the last step.

Patch test first

If your skin is sensitive, try a small area for a few days before using it all over.

Mention other actives

Tell your provider if you use retinoids or other active skincare, since combining products can increase irritation.

Begin your journey with DripVitals

Every wellness journey is different, and so are our customized NAD+ face cream routines.

Get started
  1. STEP #1

    Select your treatment

    Choose a plan that fits your needs and complete a medical intake form for review by providers.

  2. STEP #2

    Provider evaluation

    A licensed provider reviews your skin to determine if NAD+ face cream is right for you — all online.

  3. STEP #3

    Your medication, delivered

    If approved, your NAD+ face cream ships in 3–5 days with discreet packaging, so you can start your journey.

NAD+ Face Cream Safety, Side Effects, and Eligibility

Like any skincare product, NAD+ face cream can cause reactions in some people, and they are not appropriate for everyone. Reviewing the following with a licensed provider is an essential part of treatment.

Potential side effects

Most people tolerate topical nicotinamide well. Because it is applied to the skin, the most common effects are local: mild redness, warmth, tingling, dryness, or irritation, especially when first starting. Patch-testing a small area first can help. Stop use and contact your provider if you develop significant irritation, and seek medical attention for signs of an allergic reaction.

Who Should Not Use NAD+ Face Cream?

Tell your provider if you have sensitive skin, a history of skin allergies or eczema, active skin infections, or use prescription retinoids or other active skincare, since combining products can increase irritation. If you are pregnant or breastfeeding, discuss any skincare regimen with your provider first. A provider will review your skin and history to decide whether this cream is appropriate. Your provider reviews your history and will decline treatment when it is not safe or appropriate. Not everyone who applies will qualify.

Drug-interaction review

Share a complete list of your prescriptions, over-the-counter products, vitamins, and supplements during your consultation so your provider can check for potential interactions. Never start, stop, or change a medication without talking to a licensed provider.

When to contact a medical provider, and why results vary

Contact your provider if you experience side effects, have questions about dosing, or notice anything unexpected. Individual results vary based on your health, the plan prescribed, and many factors outside any single treatment, and no specific outcome is guaranteed.

Compounded medications are not FDA-approved. The FDA does not review compounded medications for safety, effectiveness, or quality before they are marketed. A licensed provider determines whether a compounded medication is appropriate based on an individual patient’s medical needs.

Comparison

Topical vs. Systemic NAD+

NAD+ is available in different forms. This face cream is a topical skincare product that acts at the surface of the skin — it is not the same as systemic NAD+ therapies (such as injections, IV, or nasal products) that aim to affect the whole body. Topical use targets the look and feel of the skin; it does not deliver the systemic effects some other NAD+ products are used for. A provider can explain the differences.

NAD+ Face CreamThis treatment

NAD+ Face Cream

Systemic NAD+

Systemic NAD+

Form

Topical facial cream

Form

Injection, IV, or nasal

Acts on

Skin surface

Acts on

Whole body

Goal

Look and feel of skin

Goal

Systemic wellness support

ApprovalCompounded, not FDA-approvedBoth
Provider reviewRequiredBoth

Neither option is universally superior — the right choice depends on your medical history and goals, and a licensed provider can help you decide.

Comparison

NAD+ Cream and Other Skincare Actives

Nicotinamide is often used alongside other well-known skincare ingredients such as retinoids, vitamin C, and peptides, each of which targets the skin differently. Nicotinamide is generally considered gentle and pairs well with many routines, though combining several actives can increase irritation for some people. A licensed provider can help you build a routine that fits your skin and goals.

Why Choose a Clinician-Guided NAD+ Face Cream?

  • Structured dosing and check-ins with your care team
  • Includes support for nutrition, sleep, and movement goals
  • 24/7 access to messaging with your care team
  • Monthly check-ins and as-needed dosage adjustments when clinically appropriate
  • Plans designed to stay affordable

Program

NAD+ Face Cream Cost & What’s Included

A DripVitals NAD+ face cream program is a clinician-guided subscription that bundles your care and medication. Depending on what your provider prescribes, it typically includes:

  • Online medical consultation and licensed-provider review
  • NAD+ Face Cream bottleYour prescribed medication from a licensed pharmacy
  • NAD+ Face Cream bottleMedication with clear usage instructions
  • Free, discreet shipping
  • Ongoing messaging access to your care team
  • Follow-up check-ins with dose adjustments when clinically appropriate
  • A subscription you can cancel at any time
  • Ready when you areStart your evaluation

Simple, transparent pricing

Your plan includes your provider consultation, medication if prescribed, medication and usage instructions, and free discreet shipping. Cancel anytime.

As low as

$119/mo

A licensed provider determines whether treatment is appropriate based on your individual medical needs. NAD+ face cream is used alongside diet and exercise. Individual results vary.

Dr. Emmanuel Noel Cruz Tancinco, MD, medical reviewer

Medically Reviewed

Dr. Emmanuel Noel Cruz Tancinco, MD

Attending Physician · ABAARM · FAAMM · DABOM

Board-certified in obesity medicine and internal medicine, with practice focused on hormone optimization, metabolic medicine, and longevity-focused care — licensed in all 35 states we serve.

  • Hormone Optimization
  • Obesity & Metabolic Medicine
  • Longevity-Focused Care
  • Functional Medicine
Education & certifications
  • American Board of Anti-Aging and Regenerative Medicine (ABAARM)
  • Anti-Aging Metabolic Medicine, American Academy of Anti-Aging Medicine
  • American Board of Obesity Medicine (DABOM)
  • American Board of Internal Medicine
  • The Institute for Functional Medicine
  • Bioidentical Hormone Replacement Therapy certified
  • Peptide Certification / Member, International Peptide Society
  • Integrative Gastroenterology, Endocrinology, Cardiology & Neurology Certification, The George Washington University School of Medicine and Health Sciences
  • Member, The American Academy of Anti-Aging Medicine (A4M)
  • Member, American College of Physicians

This page was reviewed for medical accuracy. Treatment decisions are made by a licensed provider after reviewing each patient’s medical history. Last medically reviewed October 13, 2026.

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Important safety information

NAD+ Face Cream: Frequently Asked Questions

Clear, medically reviewed answers about NAD+ face cream — what they are, safety, administration, and how the program works.

Is NAD+ face cream FDA-approved?

No. Nicotinamide is a well-established skincare ingredient, but this compounded formulation is not an FDA-approved product. Compounded preparations are not reviewed by FDA before marketing. A provider determines what is appropriate.

What are the potential side effects?

Potential side effects may include mild redness, stinging, warmth, dryness, peeling, itching, breakouts, or irritation, especially when starting or combining with other active skincare products. Stop use and contact your provider if irritation is severe, persistent, or associated with swelling, rash, or signs of allergy.

Who should not use NAD+ face cream?

NAD+ face cream is not appropriate for everyone. It is generally not recommended during pregnancy or breastfeeding, for people with a known allergy to any component of the formulation, or for those with certain medical conditions. Your eligibility depends on your full medical history, current medications, and health goals. A licensed provider reviews this information and will decline treatment if it isn’t safe or appropriate for you. Not everyone who applies will qualify.

Can NAD+ face cream be used with other skincare?

Usually, but check with your provider first. Using it alongside other active skincare products, such as retinoids, exfoliating acids, or vitamin C, may increase the chance of irritation, especially when you are starting out. Share your current skincare routine and any prescription topicals during your consultation so your provider can advise how to combine them.

How is NAD+ face cream applied?

The cream is applied to clean, dry facial skin as directed by your provider, typically once or twice daily. Follow the instructions on amount and timing.

How long until NAD+ face cream works?

NAD+ face cream works gradually. Results vary. Some people may notice changes in skin feel, hydration, or texture within several weeks, while more visible changes in tone or smoothness may take longer with consistent use. NAD+ face cream is not intended to treat, cure, or prevent any disease.

What is included in the DripVitals program?

A DripVitals NAD+ face cream program typically includes your online medical consultation and provider review, your prescribed cream from a licensed pharmacy, usage instructions, free discreet shipping, ongoing messaging access to your care team, and follow-up check-ins with adjustments to your routine when clinically appropriate. Plans are offered as a subscription you can cancel at any time. Exact inclusions and pricing depend on the plan and what your provider prescribes.

Is a consultation required?

Yes. NAD+ face cream requires a prescription, so a licensed provider must review your health information before any treatment is dispensed. The consultation is completed online through a secure intake form, and your provider may follow up with questions. If treatment isn’t appropriate for you, the provider will not issue a prescription.

How is pricing determined?

Pricing depends on the treatment your provider prescribes. DripVitals NAD+ face cream is as low as $119/month, and you can pay upfront or through a buy-now-pay-later program. Your dashboard shows exactly what you’ll pay and when, with no hidden fees, and you can cancel your subscription at any time.

Disclaimer

Only available if prescribed after an online consultation with a healthcare provider. Plans are offered as a subscription service which can be canceled at any time. Actual product packaging may appear differently than shown. Physicians may prescribe compounded medications as needed to meet patient requirements. The FDA does not review or approve any compounded medications for safety or effectiveness. The statements on this page have not been evaluated by the FDA. Results may vary. If you notice any side effects while using this treatment, contact your healthcare provider immediately.

Start your online evaluation

NAD+ Face Cream from $119/mo. A licensed clinician reviews your answers.